Vaginal Estrogen and Pelvic Floor Physical Therapy in Women With Symptomatic Mild Prolapse
Status:
Recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
This is a randomized controlled trial in which women with symptomatic mild pelvic organ
prolapse undergoing Pelvic Floor Physical Therapy (PFPT) receive vaginal estrogen versus
placebo to see if a combined approach to treatment leads to improvement in clinical outcomes.
The investigators predict that PFPT in combination with vaginal estrogen will lead to
decreased pelvic floor symptoms and improved anatomical support corroborated by biomarker
data.
Phase:
N/A
Details
Lead Sponsor:
Pamela Moalli University of Pittsburgh
Collaborators:
American Urogynecologic Society Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Institutes of Health (NIH) Pfizer