Vaginal Estrogen for the Treatment of Faecal Incontinence in Women

• Status: Terminated
• Trial end date: 2011-10-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study will address the following questions:

• Does the use of oestrogen inserted vaginally with an applicator, help with the symptoms of faecal (bowel) incontinence in women who are past the age of menopause?

• Do women find it easy to use?

• Is the treatment safe for the womb lining?

• Is there any systemic absorption of the treatment?

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: London North West Healthcare NHS Trust
• Treatments: Estradiol; Estradiol 17 beta-cypionate; Estradiol 3-benzoate; Estradiol valerate; Polyestradiol phosphate

Criteria

Inclusion Criteria:

• Post menopausal women with faecal incontinence

Exclusion Criteria:

• No hormone replacement therapy (HRT) for at least 8 weeks prior to screening

• Diabetes mellitus

• Neurological disorder

• Terminal illness

• Current treatment for breast cancer

• Unable to give informed consent