Vaginal Isonicotinic Acid Hydrazide Prior to Diagnostic Office Hysteroscopy in Primarily Infertile Patients

• Status: Completed
• Trial end date: 2021-09-15
• Target enrollment: 0
• Participant gender: Female

Summary

To compare the effectiveness of vaginal isonicotinic acid hydrazide with placebo in minimizing the pain experienced by primarily infertile patients during diagnostic office hysteroscopy and to assess the ease of insertion of hysteroscope as reported by the hysteroscopist.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Aswan University Hospital
• Treatments: Isoniazid

Criteria

Inclusion Criteria:

• nulliparous women with primary infertility requiring a diagnostic hysteroscopy as a part of an infertility diagnosis workup

Exclusion Criteria:

• women with suspected pregnancy

• heavy vaginal bleeding

• recent pelvic infection

• those known to have hypersensitivity or contraindication to isonicotinic acid hydrazide

• those who received analgesics prior to office heavy vaginal bleeding

• recent pelvic infection

• a concomitant neurologic disease that could affect the correct evaluation of pain