Vaginal Misoprostol for Cervical Ripening Prior to Endometrial Biopsy

• Status: Withdrawn
• Trial end date: 2012-09-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine whether using Misoprostol vaginally before an office endometrial biopsy is performed, will make it easier, more successful and less painful to do the procedure.

The investigators' hypothesis is that vaginal Misoprostol 12 hours prior to endometrial biopsy will increase the ease of performing office endometrial biopsy by reducing the need to use a tenaculum or a cervical dilator to achieve passage of a biopsy pipelle.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Saskatchewan
• Treatments: Misoprostol

Criteria

Inclusion Criteria:

• Patients with abnormal uterine bleeding

• Age over 35 years

Exclusion Criteria:

• Pregnancy

• Allergy to or contraindication to prostaglandin use

• Active genital tract infections

• Bleeding disorders