Vaginal Misoprostol to Improve the Neonatal Respiratory Outcome
Status:
Unknown status
Trial end date:
2018-01-01
Target enrollment:
Participant gender:
Summary
Project summary:
Objective: To test the hypothesis that administration of vaginal Misoprostol before elective
cesarean section will improve the neonatal respiratory outcomes in late preterm and early
term neonates through induction of catecholamine surge.
Design: Randomized controlled clinical trial. Setting: Women health center ,Assiut university
hospital. Patients: mothers planned for cesarean section at 34 - 37weeks. Intervention: two
hundred and ninety two women will be randomly allocated to receive either 50 micrograms of
Misoprostol per vagina within one hour before cesarean section (study group; n= 146) or
receive nothing (control group; n = 146) .
Main outcome measure: Apgar score at 1 and 5 minutes.