Vaginal Progesterone Versus Placebo in Multiple Pregnancy

• Status: Completed
• Trial end date: 2011-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to see if daily use of vaginal progesterone will prevent preterm birth in women carrying 2 or more babies.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Calgary
• Collaborators: Calgary Health Region; Juniper Pharmaceuticals, Inc.
• Treatments: Progesterone

Criteria

Inclusion Criteria:

• Confirmed multiple pregnancy

• Ultrasound confirmed minimum of 2 live fetuses

• Gestational age 16-20 6/7 weeks

Exclusion Criteria:

• Placenta previa

• Pre-existing hypertension

• Major fetal anomaly

• Monoamniotic, monozygotic multiples

• Maternal seizure disorder

• History of, or active, thromboembolic disease

• Maternal live disease

• Breast malignancy or pathology

• Progesterone dependent neoplasia

• Plans to move to another city during pregnancy

• Sensitivity to progesterone

• Participation in other clinical trials during the pregnancy