Overview
Validation Durability Adenosine Effect in Verification Pulmonary Vein Isolation
Status:
Completed
Completed
Trial end date:
2015-06-01
2015-06-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
Adenosine is used clinically to assess permanency of electrical isolation of pulmonary veins during atrial fibrillation ablation, however, the methodology has not been validated either in terms of the reproducibility of the adenosine response or the effect on clinical outcomes, namely whether using pulmonary vein reconnection to guide additional ablation lowers rate recurrent atrial fibrillation post ablation. Study will test the hypothesis that the response to adenosine used in this manner is reproducible over time.Phase:
N/AAccepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Medical College of WisconsinTreatments:
AdenosineCriteria
Inclusion Criteria:- Patients undergoing atrial fibrillation ablation, pulmonary vein isolation by catheter
for standard clinical indications
Exclusion Criteria:
- allergy or contraindication to adenosine,
- inability to give informed consent,
- currently taking dipyridamole,
- verapamil or theophylline and
- breast-feeding mothers.