Valproate Response in Aggressive Autistic Adolescents

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This study will examine the effect of valproate, a medication used to treat seizures and bipolar disorder, on aggressive behavior in children and adolescents with autism.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Valproic Acid

Criteria

Inclusion Criteria

• Autism

• Lives in the Kansas City area

Exclusion Criteria

• Psychoactive maintenance medication

• Degenerative central nervous system disorder

• Unstable medical illness

• Seizures in the 6 months prior to study entry

• History of valproate sensitivity or previous liver disease

• History of ovarian cysts

• Low platelet count or raised liver transaminases