Valsartan/Hydrochlorothiazide Combination vs Amlodipine in Patients With Hypertension, Diabetes, and Albuminuria.

• Status: Completed
• Trial end date: 2006-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is assess if treatment with valsartan and a diuretic, hydrochlorothiazide, has beneficial effects in people with high blood pressure, diabetes, and albuminuria (protein in the urine) compared with amlodipine. In particular, the study will assess whether the treatment will decrease the stiffness of the blood vessels.

• Phase: Phase 4

Details

• Lead Sponsor: Novartis
• Treatments: Amlodipine; Hydrochlorothiazide; Valsartan

Criteria

Inclusion Criteria:

• type 2 diabetes

• elevated blood pressure and pulse pressure

• albuminuria

Exclusion Criteria:

• Severe hypertension

• History of stroke, myocardial infarction, heart failure, chest pain, abnormal heart rhythm

• Liver, kidney (not caused by diabetes), or pancreas disease

• Type 1 diabetes or uncontrolled type 2 diabetes

• Allergy to certain medications used to treat high blood pressure

Other protocol-defined inclusion/exclusion criteria may apply.