Value of Amphotericin B Inhalation for Prophylaxis of Invasive Pulmonary Aspergillosis After Renal Transplantation

• Status: Unknown status
• Trial end date: 2010-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether inhalation with aerosolized amphoterin B 10mg/d is more effective than aerosolized amphoterin B 2mg/d to reduce the incidence of invasive pulmonary aspergillosis.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Capital Medical University
• Treatments: Amphotericin B; Liposomal amphotericin B

Criteria

Inclusion Criteria:

• 65ys≥age≥18ys

• renal transplant recipients

Exclusion Criteria:

• subjects with hypersensitivity to amphotericin B

• receipt of inhalational or intravenous amphotericin B within last 30 days

• subjects with known invasive fungal infection before renal transplant

• subjects with pneumonia