Varenicline for Co-occurring Cannabis and Tobacco Use

• Status: Completed
• Trial end date: 2015-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Pilot, eight week, open-label, within-subject cross over trial of four weeks of standard clinical care (SCC) in an outpatient substance abuse treatment program and four weeks of SCC and varenicline among current and former tobacco smokers with frequent cannabis use.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Albert Einstein College of Medicine
• Treatments: Varenicline

Criteria

Inclusion Criteria:

• Able to speak English

• Uses cannabis at least 5 days in the past 7 days

• Current or former tobacco smoker

• Has not taken varenicline in the past 30 days

• Not pregnant, trying to conceive or breastfeeding

• Able to provide informed consent

• Test positive for cannabinoids by urine toxicology

Exclusion Criteria:

• Unstable medical or psychiatric illness

• Opioid use disorder was initially exclusionary but eligibility criteria were revised after 32 individuals were screened to facilitate recruitment.