Overview

Vascular Dysfunction in Black Individuals: Roles of Nitric Oxide and Endothelin-1

Status:
Recruiting

Trial end date:
2022-05-01

Target enrollment:

Participant gender:

Summary

The research aims of this proposal are: - Specific Aim 1: To test whether an increase in nitric oxide signaling can increase vasodilator responses in young Black individuals. - Specific Aim 2: To test whether a decrease in endothelin-1 signaling can increase vasodilator responses in young Black individuals.

Phase:

Early Phase 1

Details

Lead Sponsor:

University of Mississippi Medical Center

Treatments:

Bosentan
Sildenafil Citrate