Vascular Effects of Sertraline in Heart Failure

• Status: Terminated
• Trial end date: 2009-07-01
• Target enrollment: 0
• Participant gender: All

Summary

To determine the effects of chronic sertraline treatment on brachial artery flow-mediated dilation in patients with chronic heart failure and depression

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yale University
• Collaborator: Pfizer
• Treatments: Sertraline

Criteria

Inclusion Criteria:

• Chronic heart failure with LVEF<40%, age >21 years

• Depression requiring medical treatment with sertraline

Exclusion Criteria:

• Known intolerance of sertraline