Vascular Endothelial Protection Effects of Dextromethorphan

• Status: Completed
• Trial end date: 2005-12-01
• Target enrollment: 0
• Participant gender: Male

Summary

To test the hypothesis that DM could have anti-inflammatory effect and thus achieve vascular protection effect on heavy smokers.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Cheng-Kung University Hospital
• Treatments: Dextromethorphan

Criteria

Inclusion Criteria:

• healthy male volunteers who are currently smoking

Exclusion Criteria:

• personal history of hypertension or diabetes mellitus

• family history with

• documented premature cardiovascular events

• cardiovascular-associated sudden death

• total cholesterol > 240 mg/dL

• triglyceride > 200 mg/dL

• low-density lipoprotein > 160 mg/dL.