Vascular Function and Uterine Fibroids

• Status: Completed
• Trial end date: 2018-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to learn how uterine fibroids may be connected to heart disease and high blood pressure. It is not known what causes fibroids, but they frequently occur in women who also have high blood pressure, heart disease, and stroke. The investigators of this study want to learn if certain changes in the blood vessels or nerve activity can put women at risk for these diseases and for fibroids.

• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Mayo Clinic
• Treatments: Acetylcholine; Nitroprusside; Norepinephrine; Oxymetazoline; Phenylephrine

Criteria

Inclusion Criteria:

• Women 25-50 years old

• Premenopausal

Exclusion Criteria:

• Postmenopausal

• Pregnant or currently breastfeeding

• Using blood pressure medications or anti-depression medications

• High blood pressure

• Diabetes

• Disease in the kidneys, lungs, or blood vessels

• Chronic diseases (for example: Crohn's disease, rheumatoid arthritis, bipolar mood disorder, etc.)

• Smoker

• High cholesterol

• BMI higher than 30