Vascular and Lipid Effects of Omega-3 Fatty Acids in People With Moderately Elevated Triglycerides

• Status: Completed
• Trial end date: 2009-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the cardiovascular and lipid effects of two doses of an omega-3 fatty acid concentrate in a group of people who normally are not treated for high lipids.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Penn State University
• Collaborator: Reliant Pharmaceuticals

Criteria

Inclusion Criteria:

• triglycerides 150-500 mg/dL

• age 21-65 years

• generally healthy

• body mass index (BMI) 20-39 kg/m2

Exclusion Criteria:

• smoking

• premenopausal (if female)

• use of hormone replacement or oral contraceptives

• use of lipid lowering or blood pressure medication

• hypertension (blood pressure > 150/95 mm Hg)

• peripheral vascular disease

• heart disease, diabetes, or stroke

• inflammatory disease (e.g. rheumatoid arthritis or Crohn's)

• elevated liver enzymes

• high intake of omega-3 containing foods

• allergy to adhesive or latex

• use of aspirin, anticoagulants, or SSRI