Overview

Vasopressin, Epinephrine, and Steroids for Cardiac Arrest

Status:
Completed
Trial end date:
2010-11-01
Target enrollment:
Participant gender:
Summary
The simultaneous activation of adrenergic and vasopressin receptors, in conjunction with a potential steroid-mediated enhancement of the vascular reactivity to epinephrine may have beneficial effects in patients with cardiac arrest. This hypothesis is supported by the single-center results of NCT 00411879. The investigators intend to either refute or provide definitive evidence supporting this hypothesis (and its generalizability) by conducting the present multicenter, randomized, controlled clinical trial of in hospital cardiac arrest.
Phase:
Phase 3
Details
Lead Sponsor:
University of Athens
Collaborator:
University of Thessaly
Treatments:
Arginine Vasopressin
Cortisol succinate
Epinephrine
Epinephryl borate
Hydrocortisone
Hydrocortisone 17-butyrate 21-propionate
Hydrocortisone acetate
Methylprednisolone
Methylprednisolone acetate
Methylprednisolone Hemisuccinate
Prednisolone
Prednisolone acetate
Prednisolone hemisuccinate
Prednisolone phosphate
Racepinephrine
Vasopressins