Vasopressin Injection Versus Misoprostol During Hysteroscopic Myomectomy In Reducing Blood Loss And Operation Time.

• Status: Completed
• Trial end date: 2017-03-15
• Target enrollment: 0
• Participant gender: Female

Summary

A prospective randomized study designed to compare the efficacy of transcervical vasopressin injection versus vaginal misoprostol in reducing intra -operative blood loss during hysteroscopic mymectomy .

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Zagazig University
• Treatments: Arginine Vasopressin; Misoprostol; Vasopressins

Criteria

Inclusion Criteria:

• symptomatic women presented with bleeding or infertility and scheduled for hysterscopic myomectomy

• grade 0 and grade 1 submucous myomas

• less than 5 centimeters in diameter

Exclusion Criteria:

• Patients with grade 2 submucous myoma or more

• patients with submucous myomas larger than 5 cm in diameter

• postmenopausal women

• patients received GnRh analogue in last 6 months

• patients with anticoagulant therapy

• patients with endometrial premalignant or malignant pathologies

• patients with cardiovascular diseases, asthma or impaired kidney functions