Vasopressor Prophylaxis After Spinal Anesthesia

• Status: Completed
• Trial end date: 2018-12-10
• Target enrollment: 0
• Participant gender: Female

Summary

Norepinephrine has been recently introduced as a prophylactic vasopressor during Cesarean delivery with promising results ; However, the optimum dose for efficient prophylaxis with the least side effects is not known. In this study, we will compare three doses (0.05, 0.1, 0.15 mcg/Kg/min) of norepinephrine for prophylaxis against Post-Spinal hypotension during cesarean delivery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University
• Treatments: Anesthetics; Bupivacaine; Norepinephrine

Criteria

Inclusion Criteria:

• full term singleton pregnant women

• Scheduled for elective Cesarean Delivery

• Aged between 18 and 40 years

Exclusion Criteria:

• Cardiac morbidities

• Hypertensive disorders of pregnancy,

• Peripartum bleeding

• Baseline systolic blood pressure (SBP) < 100 mmHg

• Body mass index > 35