Verification of the Efficacy/Safety of the Dual Drug Delivery for Hearing Loss

• Status: Recruiting
• Trial end date: 2022-02-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is a prospective, randomized pilot study. To verify an efficacy and safety of the dual drug injectable delivery vehicle, patients who have not responded to the existing standard treatment will be enrolled. Hearing test and endoscopy of tympanic membrane will be conducted after intratympanic treatment for evaluation.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Treatments: Dexamethasone; Hyaluronic Acid

Criteria

Inclusion Criteria:

• Sudden hearing loss, ototoxic hearing loss, noise-induced hearing loss, meniere's disease patients with 25dB HL in pure tone audiometry

• Patients whose hearing has not been restored after standard treatment

• Patients do not participate in clinical trials within 6 months

Exclusion Criteria:

• Patients with retrocochlear lesion

• Patients with history of hypersensitivity to the substance of this drug