Very Low Dose Oral Anticoagulation and Thromboembolic and Bleeding Complications

• Status: Terminated
• Trial end date: 2013-11-01
• Target enrollment: 0
• Participant gender: All

Summary

We aim to investiagte whether very low dose self management of oral anticoagulation is superior to low dose oral anticoagulation in order to prevent bleeding events in patients undergoing mechanuical heart valve replacement.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Heart and Diabetes Center North-Rhine Westfalia
• Collaborators: Klinikum Ludwigshafen; University of Kiel
• Treatments: Phenprocoumon

Criteria

Inclusion Criteria:

• Mechanical heart valve recipients

Exclusion Criteria:

• Contra-indication to phenprocoumon

• Ulcerous disease with bleeding tendency,

• Hypo- or hypercoagulability

• Dementia

• Missing informed consent