Very-Low Nicotine Cigarettes and Non-Daily Smokers

• Status: Completed
• Trial end date: 2017-07-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this research study is to investigate the impact of different nicotine levels in cigarettes among non-daily smokers. This research may help inform the Food and Drug Administration (FDA) on how best to regulate tobacco products in the future, with the goal of improving public health.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Saul Shiffman; University of Pittsburgh
• Collaborator: National Cancer Institute (NCI)
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• age 18 years or older, and smoking cigarettes for at least 3 years

• smoking, on average, 4-27 days per month

• smoking at current rate for at least the previous 3 months

• willingness to try novel cigarettes

Exclusion Criteria:

• active plans to quit or actively seeking smoking cessation treatment in the next 3 months

• severe psychiatric disorders that may interfere with study procedures

• current, regular (i.e., monthly or more) use of nicotine replacement or other tobacco products, by self-report

• exclusive use of roll-your-own cigarettes (since the study uses manufactured cigarettes)

• [for female participants] being pregnant or breastfeeding, or planning to become pregnant, by self-report

• current use of medications such as Chantix (varenicline), Zyban, Wellbutrin, or bupropion for any purpose, including stopping smoking

• occurrence of heart attack, stroke, or angina in the past 3 months