Overview

Vigil™ + Nivolumab in Advanced Non-Small Cell Lung Cancer

Status:
Withdrawn
Trial end date:
2017-03-01
Target enrollment:
Participant gender:
Summary
This is an open label phase 2 study to evaluate the combination of Vigil™ and nivolumab in advanced or metastatic NSCLC that is progressive on or after one prior platinum-based systemic therapy. Patients meeting study eligibility criteria will receive Vigil™ every 2 weeks (for a minimum of 4 and a maximum of 12 doses) and nivolumab every 2 weeks. The combination of Vigil™ and nivolumab will demonstrate a higher objective response rate (ORR) than the historical ORR of single agent nivolumab in patients with advanced NSCLC.
Phase:
Phase 2
Details
Lead Sponsor:
Gradalis, Inc.
Treatments:
Antibodies, Monoclonal
Armodafinil
Modafinil
Nivolumab