Overview

Virological and Clinical Anti-Hepatitis B Virus (HBV) Efficacy of Tenofovir and Emtricitabine in Patients With HIV/HBV co-Infection

Status:
Completed

Trial end date:
2006-08-01

Target enrollment:

Participant gender:

Summary

This is a randomized multicentre trial of emtricitabine (FTC) versus tenofovir (TDF)/FTC in antiretroviral naive subjects with HIV/HBV co-infection over 48 weeks (Clinical Trial A). Plus, a 12 week viral kinetic substudy comparing a subgroup of patients on Clinical Trial A is being conducted. (Substudy A1)

Phase:

Phase 4

Details

Lead Sponsor:

International Antiviral Therapy Evaluation Center

Collaborator:

Gilead Sciences

Treatments:

Efavirenz
Emtricitabine
Tenofovir
Zidovudine