Vitamin A Supplementation With Routine Childhood Vaccines and Mortality and Morbidity
Status:
Unknown status
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
Vitamin A supplementation (VAS) is important for the immune system and may interact with
different childhood vaccinations. We have hypothesized that the improved survival after VAS
may depend on vitamin A amplifying the non-specific immune modulation induced by
vaccinations.
In the present study we used information collected in connection with a national vitamin A
campaign in Guinea-Bissau during which different doses of VAS was provided together with
missing doses of DTP, OPV, and measles vaccines. We aimed to study the potential interactions
between VAS and vaccine type.