Vitamin A given as treatment and pre-treatment has reduced the severity of symptoms after
infusion with endotoxin in several animal models. We intend to examine the effect of vitamin
A as pre-treatment on the response to endotoxin in humans. We furthermore wish to examine the
long-term effects of vitamin A on the response to endotoxin. We hypothesise that vitamin A
decreases endotoxin levels and TNF-alfa responses.
Phase:
N/A
Details
Lead Sponsor:
Bandim Health Project
Collaborators:
Institute for Human Nutrition, Royal Veterinary School, Copenhagen, Denmark Uppsala University Hospital