Vitamin C as an Adjunct in Periodontal Treatment in Type 2 Diabetes Mellitus Patients

• Status: Unknown status
• Trial end date: 2018-08-19
• Target enrollment: 0
• Participant gender: All

Summary

Periodontitis patients with uncontrolled type 2 diabetes mellitus will receive non-surgical periodontal treatment and then be supplemented with daily 500 mg vitamin C (test group) or placebo (control group) for 2 months. Clinical parameters will be retrieved at baseline, at the end of week 4 and at the end of week 8.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mahidol University
• Treatments: Ascorbic Acid; Vitamins

Criteria

Inclusion Criteria:

• uncontrolled type 2 diabetes mellitus

• periodontitis

Exclusion Criteria:

• complications from diabetes mellitus, e.g., renal insufficiency

• receive insulin

• diseases that interfere with wound healing, e.g., HIV

• receive one of the followings: tetracycline, acetaminophen, NSAID, warfarin, aluminum-containing antacids, barbiturates, phenobarbital, pentobarbital, secobarbital, hormone replacement therapy, chemotherapeutic drug, protease inhibitor

• receive other vitamins or antibiotics within 6 months

• smoking

• pregnancy