Vitamin D Homeostasis in Sarcoidosis

• Status: Active, not recruiting
• Trial end date: 2023-12-30
• Target enrollment: 0
• Participant gender: All

Summary

This study evaluates the relationship between vitamin-D status and severity of sarcoidosis, and the effects of vitamin-D repletion in vitamin-D insufficient patients with sarcoidosis. Half the patients with sarcoidosis who are vitamin-D insufficient will receive standard vitamin-D supplementation via standard regimen while the other half will receive a placebo. Sarcoidosis patients who are vitamin-D sufficient will also act as controls.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Texas Southwestern Medical Center
• Treatments: Calcium; Calcium, Dietary; Citric Acid; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Stable medical condition defined as no hospitalization or emergency room visit in the previous 3 months

• No evidence of active pulmonary or systemic infection

• No other active inflammatory disease,

• No active malignancy.

• Normal serum ionized calcium level

Exclusion Criteria:

• Hospitalization or emergency room visit in the previous 3 months

• Evidence of active pulmonary or systemic infection

• Evidence of active other inflammatory disease

• Evidence of active malignancy

• Elevated serum ionized calcium level