Vitamin D Oral Gel for Prevention of Radiation Induced Oral Mucositis

• Status: Recruiting
• Trial end date: 2020-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The main aim of this study was to evaluate clinically the effect of topical oral vitamin D gel in comparison to conventional therapy in prevention of radiation - induced oral mucositis

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Hams Hamed Abdelrahman
• Treatments: Ergocalciferols; Miconazole; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Patients who are going to receive radiotherapy as a treatment of head and neck cancer either as postoperative (adjuvant) therapy or definitive therapy.

• Patients whose radiotherapy treatment planned dose is 50 Gy or above.

• Patients receiving radiotherapy alone or receiving concomitant cisplatin (or carboplatin) with radiotherapy.

Exclusion Criteria:

• Patients under Anticoagulants such as warfarin, heparin, or aspirin.

• Patients whose radiotherapy treatment planned dose is lower than 50 Gy.

• Patients suffering from any uncontrolled systemic diseases (such as diabetes, cardiovascular, liver disorder, renal dysfunction)

• Patients with findings of any physical or mental abnormality which would interfere with or be affected by the study procedure.

• Hyper-calcemic patients.

• Smokers.