Vitamin D Replacement: The Effect on Statin-Related Myalgias

• Status: Terminated
• Trial end date: 2011-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this project is to determine if Vitamin D supplementation [10,000 international units of cholecalciferol (vitamin D3) by mouth weekly] will decrease the rate of discontinuation of statin therapy due to muscle ache/pain and decrease the occurrence of muscle ache/pain due to statin therapy.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Creighton University
• Treatments: Cholecalciferol; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Patients who recently prescribed statins (in the last seven days) or who have had a recent increase in statin dose (in the last seven days)

• Patients aged 19-89 years old

• Men and women (not of childbearing potential)

• Patients receiving statins with concomitant ezetimibe

Exclusion Criteria:

• history of alcoholism or malnutrition

• receiving concomitant niacin, fibric acid derivatives, bile acid sequestrants, or other drugs that affect cholesterol levels