Vitamin D Treatment in Ulcerative Colitis

• Status: Withdrawn
• Trial end date: 2014-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to test blood and tissue samples of people with Ulcerative Colitis (UC) to see what effects Vitamin D3 may have on the immune system. This research is being done because it could lead to the development of new treatment for people with Inflammatory Bowel Disease (IBD).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Chicago
• Collaborator: North Shore University Hospital
• Treatments: Cholecalciferol; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Patients must be over 18 years of age

• have a diagnosis of UC as confirmed by histology.

• UC patients must have active but mild disease as confirmed by a Mayo Clinic endoscopy score from 2-4,

• not requiring medication adjustment during the trial.

• Patients must be capable of understanding the purpose, risks and expectations of study participation and willing to provide written informed consent.

Exclusion Criteria:

• Individuals on vitamin D or laxative therapy (except for purposes of endoscopy preparation),

• UC patients with fulminant colitis or active C difficile or other colonic infections,

• age<18 year old,

• individuals with bleeding disorders will be excluded from the study.