Vitamin D and Muscle Strength and Surface (Electromyography) EMG
Status:
Completed
Trial end date:
2011-04-01
Target enrollment:
Participant gender:
Summary
Vitamin D deficiency is widely prevalent in India. Serum 25(OH)D levels are <20 ng /ml in up
to 90% of them. Recently, in a randomized control trial, investigators have shown that dual
cholecalciferol and calcium supplementation lead to significant improvement in hand grip
strength and distance covered during six minutes walk test. Present study is being taken to
further understand the functional significance of 25(OH)D in terms of its effect on Skeletal
muscle strength including surface electromyography (EMG) in a larger cohort involving
approximately 200 subjects. The impact of calcium and vitamin D supplementation would be
assessed by supplementing them alone and in combination. Besides, the investigators would
also assess impact of above supplementation on Th1/Th2 cytokines expression in the peripheral
mononuclear cells.
Phase:
Phase 3
Details
Lead Sponsor:
Indian Council of Medical Research
Treatments:
Calcium Calcium Carbonate Calcium, Dietary Cholecalciferol Ergocalciferols Vitamin D Vitamins