Vitamin D and Physical Performance Before and After Intervention and Birth Outcome in Pregnant Somali and Swedish Women
Status:
Completed
Trial end date:
2016-08-01
Target enrollment:
Participant gender:
Summary
Somali migrant women, often in veiled clothing, living in a town in mid Sweden on the 60:th
parallel were observed to be weak and to have a waddling gate.
Study 1 was carried out in the setting of an antenatal clinic administered from a primary
care center in Borlänge, a Swedish middle-sized industrial town at the 60:th parallel in
Sweden. The investigators chose an initial study period in late spring to reflect the effects
of the dark season with little ultraviolet B radiation that affects vitamin D production.
Study 1 was carried out in a short period of time. The recruitment was performed in a
retrospective design in order to neglect the seasonal effects of ultraviolet B radiation.
Study 1 was carried out in year 2010. It was a cross sectional baseline study of blood levels
of vitamin D measured as 25-hydroxyvitamin D (25-OHD) and physical performance in 123
pregnant and new mothers from Somalia (n=52) and Sweden (n=71).
Study 2: Examines the results on muscular performance, i.e. grip strength and squatting
ability, from intervention with advice and prescription of vitamin D3 and calcium for 10
months, in all the women from study 1 with 25-OHD levels <50 nmol/L or 50 nmol/L of 25-OHD.
Study 3: The recruitment to Study 1 also serves as recruitment for a cohort study on delivery
outcome in birth protocols starting 2016.
Study 4: The aim is to study the emic perspective and lifestyle related to vitamin D and
strength in the group of Somali women by focus interviews among the Somali women from above.
A possible fifth study will explore correlations between 25-OHD and pain distribution and
pain parameters.
Phase:
N/A
Details
Lead Sponsor:
Uppsala University
Treatments:
Calcium Calcium Carbonate Calcium, Dietary Cholecalciferol Ergocalciferols Vitamin D Vitamins