Vitamin D for Chemoprevention

• Status: Completed
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will help us know the effects of Vitamin D pills in Blacks. The results of this study may be the first step in creating ways to prevent the risks of colon and prostate cancer. It will also help us develop ways to reduce colon cancer and prostate cancer among Blacks. This study will find out if Vitamin D pills can increase Vitamin D to healthy levels in our bodies.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Dana-Farber Cancer Institute
• Collaborators: Harvard School of Public Health; Harvard School of Public Health (HSPH)
• Treatments: Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Between the ages of 30 and 80 years

• Comfortable communicating in English

• Currently has a primary care physician

• Willing to discontinue vitamin D or calcium supplements

• Willing to have all protocol specific tests run

Exclusion Criteria:

• Plans on taking a vacation or travel to a sunny region within 3 months of vitamin supplementation period except for a short period (i.e. 1 weekend)

• Pregnant or breast feeding or planning on becoming pregnant in the following year

• Pre-existing calcium (including hypercalcemia), parathyroid conditions (including hyperparathyroidism), sarcoidosis

• No concurrent active malignancies (other than non-melanoma skin cancer) or previous diagnosis of prostate cancer

• Cognitively impaired

• Active thyroid disease (e.g. Graves, Hashimoto's or thyroiditis)

• History of nephrolithiasis, chronic liver disease, chronic renal disease, or renal dialysis