Vitamin D in Bronchiolitis Obliterans Syndrome

• Status: Completed
• Trial end date: 2015-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Vitamin D deficiency occurs in around 50% of our transplant population. Preventive treatment with Vitamin D (D-cure) can reduce the prevalence of Bronchiolitis Obliterans Syndrome after lung transplantation

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Universitaire Ziekenhuizen Leuven
• Collaborators: Katholieke Universiteit Leuven; KU Leuven
• Treatments: Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Stable LTx recipients at discharge after transplantation.

• Signed informed consent

• Adult (age at least 18 years old at moment of transplantation)

• Able to take oral medication

Exclusion Criteria:

• Prolonged and/or complicated Intensive care unit-course after transplantation.

• Early (<30 days post-transplant) post-operative death

• Major suture problems (airway stenosis or stent)

• Retransplantation (lung)

• Previous transplantation (solid organ)

• Multi-organ transplantation (lung+ other solid organ)