Vitamin D3 Effects on Musculoskeletal Symptoms With Use of Aromatase Inhibitors

• Status: Completed
• Trial end date: 2015-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

The Purpose of this study is to determine whether vitamin D3 supplements will decrease the muscle and bone pain that are reported by women who take Aromatase Inhibitors.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: HealthPartners Institute
• Collaborators: University of Minnesota; University of Minnesota - Clinical and Translational Science Institute; University of Southern California
• Treatments: Aromatase Inhibitors; Cholecalciferol; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Age ≥ 18 years

• Women with a history of stage I-IIIa invasive breast cancer

• History of hormone-receptor positive cancer (either ER + or PR + or both)

• Are prescribed and are taking anastrozole, letrozole or exemestane for at least one month and have at least 7 months of AI treatment remaining

• Are experiencing AIMSS

Exclusion Criteria:

• Unable to read or understand English

• History of psychiatric disability affecting informed consent or compliance with drug intake

• Malabsorption syndrome or inability to take oral medication

• Has less than 7 months of AI therapy remaining