In this study, we want to find out if laughing gas (nitrous oxide) leads to a higher rate of
cardiac complications after surgery in patients with a specific genetic profile (mutations in
the MTHFR gene) and if this risk can be prevented by giving patients vitamin B12 and folate
during surgery.
Phase:
N/A
Details
Lead Sponsor:
Washington University School of Medicine
Collaborators:
Foundation for Anesthesia Education and Research National Institute of General Medical Sciences (NIGMS)
Treatments:
Folic Acid Hydroxocobalamin Nitrous Oxide Vitamin B 12 Vitamin B Complex Vitamins