Vonoprazan in Helicobacter Pylori Treatment an RCT

• Status: Completed
• Trial end date: 2021-08-16
• Target enrollment: 0
• Participant gender: All

Summary

RCT for comparison of Standard Triple therapy (Omeprazole+Amoxil+Clarithromycin) for H Pylori erradication with Vonoprazan+Amoxil dual therapy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Dow University of Health Sciences
• Treatments: Amoxicillin; Clarithromycin; Omeprazole

Criteria

Inclusion Criteria:

• Helicobacter Pylori Positive by any one of following:

Histopathology by Giemsa Stain Stool Antigen

Exclusion Criteria:

• • Previous surgery of the stomach such as partial gastrectomy.

• Allergy to any of the antibiotics used in the study.

• Intake of antibiotics, PPIs, corticosteroids, or nonsteroidal anti-inflammatory drugs within the last 2 weeks.

• Pregnant or lactating females.

• Alcohol abuse or drug addiction.

• Severe neurological or psychiatric disorder.