Overview

Vorinostat and Lenalidomide After Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma

Status:
Completed
Trial end date:
2020-05-04
Target enrollment:
Participant gender:
Summary
RATIONALE: Vorinostat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Lenalidomide may stop the growth of multiple myeloma by blocking blood flow to the cancer. Giving vorinostat together with lenalidomide may kill more cancer cells. PURPOSE: This phase I trial is studying the side effects and best dose of vorinostat when given together with lenalidomide after autologous stem cell transplant in treating patients with multiple myeloma.
Phase:
Phase 1
Details
Lead Sponsor:
Ohio State University Comprehensive Cancer Center
Collaborator:
Merck Sharp & Dohme Corp.
Treatments:
Lenalidomide
Thalidomide
Vorinostat