Vytorin on Carotid Intima-media Thickness and Overall Rigidity
Status:
Completed
Trial end date:
2005-12-01
Target enrollment:
Participant gender:
Summary
Comparison of the effect on the progression of the carotid intima-media interphase thickness
(GIM), arterial rigidity according to the measurement of the pulse wave speed and direct
measurement of the carotid and aortic rigidities and an inflammation marker (PCR) in patients
with established cardiovascular disease (myocardial infarct, atherosclerotic coronary
disease), diabetes mellitus type 2 or equivalent risk of coronary disease and a low density
lipoprotein level > 100 mg/dL, treated with simvastatin, pravastatin or the combination of
simvastatin-ezetimibe during a period of at least one year.
Phase:
Phase 4
Details
Lead Sponsor:
Hospital Universitario 12 de Octubre
Collaborator:
Merck Sharp & Dohme Corp.
Treatments:
Ezetimibe Ezetimibe, Simvastatin Drug Combination Pravastatin Simvastatin