Overview

WIRE - Novel Treatments in Renal Cell Cancer

Status:
Recruiting
Trial end date:
2022-04-25
Target enrollment:
Participant gender:
Summary
Evaluation of proof of mechanism with relation to ktrans and/or CD8 count when 3 different IMPs are given as monotherapy or as combination therapy. These would be administered in the "window of opportunity", prior to nephrectomy in surgically resectable renal cell cancer
Phase:
Phase 2
Details
Lead Sponsor:
CCTU- Cancer Theme
Collaborators:
AstraZeneca
Cancer Research UK
University of Cambridge
Treatments:
Antibodies, Monoclonal
Cediranib
Durvalumab
Olaparib