Warfarin Initiation in Mechanical Mitral Valve Replacement Patients
Status:
Completed
Trial end date:
2019-09-01
Target enrollment:
Participant gender:
Summary
A prospective, comparative study evaluating warfarin initiation in a dose of 3mg versus 5mg
in mechanical mitral valve prostheses patients who received anticoagulation with warfarin
with the use of enoxaparen as a bridging agent .Fifty patients were included and compared in
terms of the primary outcome time to reach therapeutic INR range.Other outcomes includes
proportion of patients who achieved the target INR of 2.0-3.0 between day 3 and day 5, total
dose of enoxaparin required for bridging, safety related to both doses of anticoagulants used