Weekly Vinblastine for Chemotherapy Naive Children With Progressive Low Grade Glioma (PLGGs)
Status:
Unknown status
Trial end date:
2019-10-01
Target enrollment:
Participant gender:
Summary
The overall objective of this study is to determine the efficacy of weekly Vinblastine in
chemotherapy naïve patients with progressive or incompletely resected paediatric low grade
glioma, to generate estimates of the response rate, progression-free survival, toxicity and
quality of daily living among the population treated and determine biologic factors which
will enable us to predict tumour behaviour.
Phase:
Phase 2
Details
Lead Sponsor:
The Hospital for Sick Children
Collaborators:
Brain Tumour Program Paediatric Oncology Institutions of the Canadian Paediatric Brain Tumour Program Pediatric Oncology Group of Ontario