Weighted Versus Uniform Dose of Tranexamic Acid in Patients Undergoing Primary, Knee Arthroplasty
Status:
Completed
Trial end date:
2015-03-01
Target enrollment:
Participant gender:
Summary
Hypotheses: Primary - A weighted dose of 20 mg/kg of tranexamic acid will be more efficacious
than a single uniform dose of 1 gram in primary total knee arthroplasty (TKA) cases. This
includes having a greater impact on decreasing blood loss without increasing the occurrence
of adverse thromboembolic events in patients undergoing primary, elective total knee
arthroplasty.
Secondary - TA will decrease blood loss more effectively in women than in men undergoing this
procedure.