Overview

Withdrawal of Medication in Recovered DCM

Status:
Terminated

Trial end date:
2019-11-01

Target enrollment:
0

Participant gender:
All

Summary

Randomized study of medication withdrawal in patients who have recovered LV function in Dilated Cardiomyopathy.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

McGill University

Collaborators:

Jewish General Hospital
McGill University Health Center
McGill University Health Centre/Research Institute of the McGill University Health Centre

Treatments:

Adrenergic beta-Antagonists
Angiotensin-Converting Enzyme Inhibitors

Criteria

Inclusion Criteria:

1. Patient diagnosed with dilated cardiomyopathy (DCM) with an initial HFrEF < 40 % at
presentation.

2. DCM with recovered LV function to > or = to 50% documented on 2 ECHO examinations,
with the most recent ECHO examination within 1 year of enrolment.

3. Time from initial diagnosis of DCM more or equal to 24 month.

4. Last hospitalization for decompensated HF > 1year.

Exclusion criteria:

1. Ischemic cardiomyopathy

2. Other structural pathology such as: Hypertrophic cardiomyopathy, Valvular
cardiomyopathy or congenital heart disease.

3. Last hospitalization for decompensated HF < 1year ago.

4. Previous sustained ventricle tachycardia or ventricle fibrillation (VF) arrest.