Wound Infiltration With Local Anesthetic Agent for Laparoscopic Appendectomy in Adult
Status:
Completed
Trial end date:
2019-07-31
Target enrollment:
Participant gender:
Summary
Acute appendicitis is one of the most common acute abdomens that need surgical intervention.
Laparoscopic surgery much decreases postoperative pain of wound, however, pain remains an
important determinant of recovery after surgery. Intraoperative local anesthetic agent
infiltrated locally into surgical wound to relieve postoperative pain is a feasible and safe
method suggested in some literature. However, there is no routine use of this method in
clinical practice because its benefit is still unknown. Besides, very few evidence could be
found in literature review. To date, there is still no double blinded, prospective,
randomized control trial addressing in evaluation of its interest. In this study, the
investigators aim at investigating the benefit of wound infiltration with local anesthetic
agent (bupivacaine) for laparoscopic appendectomy in adult. The study design is a double
blind, prospective, randomized control trial with a 1:1 allocation ratio. Fifty adult
patients with appendicitis will be included. The control group undergo laparoscopic
appendectomy without wound infiltration with local anesthetic agent, the intervention group
undergo laparoscopic appendectomy with wound infiltration with local anesthetic agent
intraoperatively. The clinical characteristics, outcomes, and patient's satisfaction will be
recorded and analyzed. The investigators hope this study can provide a high level evidence in
pain management of patient undergo laparoscopic surgery.