Xian-Hua-Cha for Relieving Hyperlipidemia With Obesity

• Status: Not yet recruiting
• Trial end date: 2024-10-05
• Target enrollment: 0
• Participant gender: All

Summary

In the past decades, lipid and body fat disorders become a serious global healthcare issue, especially among the obese population. The aim of this study is to include 100 selected patients with BMI higher than 27 and hyperlipidemia, and a crossover design is used to explore the efficacy of "Xian-Hua-Cha (XHC)" on relieving hyperlipidemia among obese patient. For this purpose, the changes of patients' body weight, body fat and the metabolic parameter including blood sugar, cholesterol, triglyceride are analyzed in the end of this study.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Chang Gung Memorial Hospital

Criteria

Inclusion Criteria:

1. BMI ≧ 27kg/m2

2. Total cholesterol > 200 mg/dL or LDL > 130 mg/dL or triglyceride > 150 mg/dL

3. Age ≧ 20 years and < 75 years

4. No recognition difficulties

5. Willing to sign inform consent and comply to protocol

Exclusion Criteria:

1. Pregnant or breast-feeding women

2. Endocrine disorders (uncontrolled hypo/hyperthyroidism, adrenal gland disorder)

3. Diagnosis of neurologic or psychiatric diseases

4. Liver or renal dysfunction (AST/ALT higher than 3 times of upper normal limits; eGFR < 60 mL/min/1.73 m2)

5. Acute stress condition (severe infection, receive major surgery in the recent 1 month)

6. Vision, or hearing impairment

7. With other clinical trial medication

8. With medication for obesity or hyperlipidemia in the recent 1 month

9. Heavy smoker, alcoholism or substance abuse

10. Severe organ dysfunction: malignancies, autoimmune diseases