Overview

ZAVI APD ELF Protocol v2.2

Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
CAZ/AVI is a new antibiotic drug that is meant to be used for various indications including cIAI and nosocomial pneumonia. To date, limited data exists on PK of CAZ/AVI in patients undergoing peritoneal dialysis as well as on penetration of CAZ/AVI in ELF of critically ill patients. The present study is carried out to determine target site PK of CAZ/AVI in these two populations, in order to contribute to a more complete understanding of the drug's penetration to its site of action.
Phase:
Phase 1
Details
Lead Sponsor:
Markus Zeitlinger
Treatments:
Avibactam
Avibactam, ceftazidime drug combination
Ceftazidime