Overview

ZEN003694 Combined With Niraparib in Patients With Metastatic or Recurrent Solid Tumors

Status:
Recruiting
Trial end date:
2029-12-31
Target enrollment:
Participant gender:
Summary
This Phase I, open label, dose determining study of oral niraparib in combination with ZEN003694 given daily in 28-day cycles will enroll patients with metastatic or recurrent solid cancer. Dose escalation will follow the mTPI-2/Keyboard design. Eligible patients will receive therapy until disease progression or unacceptable toxicities are experienced.
Phase:
Phase 1
Details
Lead Sponsor:
Haider Mahdi
Collaborators:
GlaxoSmithKline
Zenith Epigenetics
Treatments:
Niraparib