Overview

Zibotentan and Dapagliflozin Combination, EvAluated in Liver Cirrhosis (ZEAL Study)

Status:
Not yet recruiting
Trial end date:
2024-11-21
Target enrollment:
Participant gender:
Summary
This is a two part Phase IIa/b multicentre, randomised, double-blind, placebo-controlled, parallel group dose-ranging study to assess the efficacy, safety, and tolerability of the combination of zibotentan and dapagliflozin, and dapagliflozin monotherapy versus placebo in participants with cirrhosis with features of portal hypertension.
Phase:
Phase 2
Details
Lead Sponsor:
AstraZeneca
Treatments:
Dapagliflozin